Advanced visualization techniques could change the paradigm for diagnosis and treatment of heart disease

ScienceDaily (May 31, 2012) ? Researchers from Mount Sinai School of Medicine are pioneering new ultrasound techniques that provide the first characterization of multidirectional blood flow in the heart. By focusing on fluid dynamics -- specifically, the efficiency with which blood enters and exits the heart's left ventricle -- the researchers believe they can detect heart disease even when traditional measures show no sign of trouble.

In addition to improving diagnoses, this shift in focus from muscle mechanics to fluid mechanics could lead to more effective therapeutic interventions. The work is described in a study published by two Mount Sinai cardiologists and a team of international collaborators in a recent issue of JACC Cardiovascular Imaging, a journal of the American College of Cardiology.

The ultrasound tools cardiologists use today often fail to detect changes in the heart until there is overt dysfunction. Blood flow imaging, however, may provide better clues in diagnosing heart failure. Sinai investigators reason that flow should be immediately affected by changes in cardiac function -- such as those revealed in image analysis by the chaotic behavior of tiny whirlpools.

The computer-aided visual study of these abnormalities could dramatically improve the assessment of patients with heart failure and lead to a fresh understanding of normal and abnormal pumping and circulatory function. Visual blood-flow analysis could also yield improved therapies for arrhythmias and other disorders requiring cardiac synchronization. Researchers are actively exploring applications in aortic atherosclerosis, before and after valve replacement, and congenital abnormalities.

"With visualization, we are looking at the ultimate measure of the efficiency of the heart -- how the blood is brought in and how it is sent out," said Jagat Narula, MD, PhD, Director of Cardiovascular Imaging at Mount Sinai and the senior author of the paper. "Today, cardiologists place great weight on a gauge called the squeeze fraction, or ejection fraction -- the portion of blood pumped from the ventricle with each heartbeat. What we are doing is a complete departure from the view of the heart as a squeezing, pressure-generating chamber."

Mount Sinai researchers and their collaborators have experimented with a range of imaging techniques to grasp the characteristics of normal and abnormal blood flow. The approaches include phase-encoded MRI, cardiac magnetic resonance (CMR) and several forms of ultrasound-based imaging known as echocardiographic particle imaging velocimetry.

"The most effective technique involves injecting a stream of bubbles that behave exactly like red blood cells and using echocardiography to track their path through the left ventricle," said Partho Sengupta, MD, Director of Cardiac Ultrasound Research at Mount Sinai, and the first author, with Narula, of the JACC paper. In these investigations, the computer-enhanced video output depicts normal and turbulent flow in vivid detail, with arrows plotting the direction as the bubbles swirl through the heart chamber.

"Not only are you following the path of the blood, but you can actually identify the amount of energy that is being distributed," said Dr. Sengupta. "Like other forms of ultrasound, that means low-cost heart tests using this technology could be performed on a simple outpatient basis."

The echocardiography technology pioneered by Sengupta and Narula sheds light on diagnostic discrepancies that have puzzled cardiologists relying on pressure measurements.

"After sustaining significant damage, a patient's heart may not have the greatest squeeze, but there could be good trafficking of blood through the heart and the patient could remain asymptomatic," Sengupta explained. "The normal ejection fraction is around 60 percent, but we sometimes see a patient with 20 percent walking around and playing golf. Other people who are at 50 percent may be short of breath. Flow visualization is one way to capture the essence of why the patient is or is not symptomatic."

Diagnosing cardiac disease by looking for structural defects in the heart is like analyzing highway traffic by examining the road, Dr. Narula said. "The structure may not be great, but how does that affect the cars that are actually traveling on the road? It's the same thing if you fail to look at the blood."

Likewise, a plumber's investigation of pipes in a house only matters or makes sense in relation to how the water flows, claims Sengupta. A new study these investigators have submitted for publication zeros in on specific correlations between blood flow and cardiac pathology. "We will be able to demonstrate that efficiency may be lost even though the structure is maintained," said Senguptra. "In other words, the fa?ade is good, but inside, you have lost it."

Sengupta points out that the combined visualization and computation techniques in the JACC paper are still new and require further work, including development of appropriate flow-based indexes for applications in various cardiac pathologies. Forces acting on flow are exceedingly complex and dynamic, the researchers said. Pumped by the heart at a rate of 8 pints to 16 pints per minute, blood interacts with the contours of the myocardium, valves, vessels, and other features, which are also in motion. The flow is multidirectional -- curling, spinning, and forming eddies that are affected in countless ways by structural changes in heart tissue. As with any new observational techniques, data from novel cardiac visualizations in complex environments are subject to interpretation.

"We have started using these imaging techniques in clinical trials," Narula said. "They will require careful evaluation."

Images of the blood flow can be viewed at: http://youtu.be/3hxa9mNlgVw.

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The above story is reprinted from materials provided by Mount Sinai Medical Center, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Christopher M. Kramer, Jagat Narula. Viability is in the Eye of the Beholder?. JACC: Cardiovascular Imaging, 2012; 5 (5): 574 DOI: 10.1016/j.jcmg.2012.04.002

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Mass. woman finds baby bird with 2 heads, 3 beaks

NORTHAMPTON, Mass. (AP) ? A Northampton woman made an unusual discovery in her yard ? a deformed baby cardinal with two heads and three beaks.

April Britt says she found the bird near the base of a tree Monday and returned it to its nest.

The 67-year-old Britt tells the Daily Hampshire Gazette (http://bit.ly/LFlSqn ) the bird apparently couldn't eat without assistance from the adult birds. The middle beak didn't work well and the other two didn't appear to be connected to the bird's throat.

A scientist for the Massachusetts Audubon Society says animals with such abnormalities rarely survive birth, making the find all the more unusual. He says the deformities could have been caused by genetic or environmental factors.

The baby and adults were gone by Tuesday.

___

Information from: Daily Hampshire Gazette, http://www.gazettenet.com

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Netflix for iOS updated with a new player UI, support for alternate language audio and more

There's still no word available on HD video streaming, but Netflix has just released version 2.2 of its app for iPhones and iPads. While the front end got tablet friendly in December and received a Retina Display makeover in March, this version brings a new player UI to all iOS devices. The new scrub bar seems much easier to reach and control now, while the button for subtitles has a received a tweak reminiscent of the new look recently pushed to Netflix's web based player. Also under that button is a new option allowing for alternate language soundtracks (where available), while the changelog goes on to mention "general performance improvements". Not documented but present is the addition of thumbnails in that scrub bar, easier access to "do not share" for Facebook-connected members and the ability to restrict streaming to WiFi-only in the settings. The new version is shown above, check after the break for a grab of the old player to see the difference. As always, the latest update can be found in the app store, we'll let you know if we hear of any extra details or changes on other platforms.

Continue reading Netflix for iOS updated with a new player UI, support for alternate language audio and more

Netflix for iOS updated with a new player UI, support for alternate language audio and more originally appeared on Engadget on Wed, 30 May 2012 21:09:00 EDT. Please see our terms for use of feeds.

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Considering The Potential Future When Contemplating Website ...

Posted on May 29th, 2012 Web Doctor

Precisely what are you really planning to do to accelerate your site promotion in the approaching months and years ahead? If the response is relatively predictable or you just want to try and embrace the status quo while you tread water, get ready for some serious wake-up calls. This business is really dynamic and will certainly represent the leading edge of marketing in general. Traditional methodology may still work, but more and more organisations and consumers are looking towards the Web in ever-growing numbers.

You may be thinking that it is enough to focus only on your search engine optimisation goals while you try and grow during 2012. There?s a lot more competition here and you?ll definitely have to engage an organisation that truly understands what works and what doesn?t in each and every way. These days it is a lot more about exactly what is on your site rather than about how exactly you are able to configure it technically so it automatically appears within the rankings.

What sort of a service or product do you offer your customers? Is your website interactive? You ought to have a really dynamic blog structure and be sure that you?re supporting comments through your viewers. Whenever men and women comment the large search engines stand up and may potentially take notice. If they can see a lot of ?to and fro? as well as positive commenting this on its own signifies a social ?signal? to them, indicating that individuals take the time to interact with you. Engagement such as this signifies that people fundamentally trust you and this is a good reason why Google should raise your site inside the search engine ranking positions to a better position.

Your own successful website promotion programmes should also catch up with twenty-first century advancements such as the proliferation of new Apps. Can you create an App for the organisation that can help to tell a story about your identity or whatever you do? Perhaps you could create an App that would be of benefit in some way for your clients? daily lives? If you?re able to, then make certain that you promote it on the site and get ready for the day when individuals will be using their mobile phones first and foremost as they search the Internet.

You may have seen that the measurement of the screen is essentially shrinking. As customers move away from desktop computer devices to smaller and more portable notepads and laptops, tablets are also gaining ground. One day we?re going to reach a pleasant medium ? possibly something between the dimensions of a smart phone and the current tablet. This will likely symbolise much of our online world in the not too distant future. Are you ready for it?

Right here, in a case where you would love to read far more that?s relevant to website promotion, don?t hesitate to have a look to acquire further information => WebsitePromotion

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1M Students Strong, Echo360 Secures $31M From Steve Case, Ted Leonsis To Flip Higher Ed

Today, four-year-old Echo360 already has 1 million students using its blended learning solutions in over 6,000 classrooms and 500 institutions, owns 54 percent of its market, and is seeing annual revenue of $15 million. However, all told, Echo360 is only currently serving about 10 percent of the colleges and universities in the U.S., and, on top of that, its leadership sees big opportunities abroad. Now, thanks to a big investment from some familiar names, Echo360 is looking to step on the accelerator. The investment comes from the $450 million Revolution Growth fund, founded by Steve Case, Ted Leonsis, and Donn Davis -- all well-known entrepreneurs and executives in their own right and each a veteran of Aol leadership. (Case being a co-founder.) The fund, which typically makes $25 to $50 million investments in companies that it can help take "from niche to mass and scale to capitalize on huge market opportunities," (i.e. disrupt big industries) sank $25 million into Vienna-based online auction company, FedBid, in January.

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Scotland Real Estate Set To Drop With End Of Stamp Duty Exemption

The stamp duty exemption for Scotland real estate purchases is at an end, and it is expected that market will see a significant drop in activity now. 38% of first time buyers in Scotland purchased homes in the ?125,000 to ?250,000 range - which was the range exempted from stamp duty. This represented the highest proportion of buyers in that range since records began. For more on this, continue reading the following article from Property Wire.

First time buyers in Scotland bought higher priced property than usual in the first quarter of 2012, taking advantage of the stamp duty concession, according to new figures from the Council of Mortgage Lenders in Scotland.

Some 38% of first time buyers in Scotland bought property valued between ?125,000 and ?250,000, the bands exempt from stamp duty during the concession. This is the highest proportion since records began in 2005.

Due to lower house prices in Scotland, around 35% of first time buyers usually buy property in these bands compared to 50% in the UK as a whole. Properties under ?125,000 were still the most popular option in Scotland in the first quarter but, at 58% of first time buyers buying within this band, this is the lowest since records began.

There were 4,000 loans, worth ?380 million, taken out by first time buyers in Scotland in the first quarter. Despite the stimulus provided by the end of the stamp duty concession, this was a 9% fall in the number of loans and a 5% fall in the value compared to the previous quarter, but a rise of 21% by number and 31% by value compared to the first quarter of 2011.
First time buyers accounted for 42% of the house purchase loans in Scotland, the highest since 2001 and the same proportion in the UK as a whole.

Scottish first time buyers typically borrowed 80% of their property's value in the first quarter of the year, the same as the UK overall. The proportion of income spent on mortgage interest payments by first-time buyers increased to 11.4% in the first quarter from 11% in the previous quarter but was still lower than the proportion paid by first time buyers across the UK which was 12.7%.

Lending to home movers followed a similar pattern to first time buyers. The 5,500 loans taken out, worth ?720 million, was a fall of 24% (25% by value) from the last quarter, but a rise of 8% (11% by value) compared to the first quarter of 2011.

Overall, Scotland experienced a fall in lending for house purchase, as in the UK, in the first quarter of 2012. 9,500 loans were taken out, worth ?1.1 billion, down from 11,600, worth ?1.4 billion, in the last three months of 2011, but up from 8,400, worth ?930 million, in the three months to March 2011.
?
Remortgage lending also dropped in the first quarter in Scotland and UK wide. There were 7,800 loans, worth ?750 million, down from 9,000, worth ?880 million, the previous quarter and 8,900, worth ?850 million, in the first quarter of 2011.

?Despite the fall in lending in Scotland in the first quarter of the year, the end of the stamp duty concession clearly had an effect on the market, mainly with the increase in the proportion of higher priced properties bought by first time buyers during this period,? said Iain Malloch, chair of CML Scotland.

?However, if Scotland follows the trend expected across the UK, there is likely to be a further drop in activity over the coming months. The CML in Scotland looks forward to working with the Scottish government and other stakeholders throughout the rest of 2012 to ensure the housing market is open for business across all tenures,? he added.

This article was republished with permission from Property Wire.

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Essential reading: Lawmakers work with Simpson-Bowles for tax ...

?

Fiscal Commission co-chairs Alan Simpson (L) and Erskine Bowles speak to reporters in Washington April 14, 2011. REUTERS/Kevin Lamarque

Welcome to the top tax and accounting headlines from Reuters and other sources.

?

* Lawmakers work with Simpson-Bowles for tax deal. Kim Dixon ? Reuters. Former Democratic White House chief of staff Erskine Bowles said he and former Republican senator Alan Simpson, are working with a bipartisan group of 47 senators and as many House members to frame a compromise on $7 trillion in looming fiscal decisions, Bowles said on CNN?s news program, ?Fareed Zakaria GPS.? Without a deal, the end of the year brings higher taxes for most Americans with the expiration of historically low income tax rates enjoyed by nearly every American and expiry of a payroll tax break, along with broad automatic spending cuts that most lawmakers in both parties want to avoid. Link

* With personal data in hand, thieves file early and often. Liaette Alvarez ? The New York Times. Besieged by identity theft, Florida now faces a fast-spreading form of fraud so simple and lucrative that some violent criminals have traded their guns for laptops. And the target is the United States Treasury. The criminals, some of them former drug dealers, outwit the Internal Revenue Service by filing a return before the legitimate taxpayer files. Then the criminals receive the refund, sometimes by check but more often though a convenient but hard-to-trace prepaid debit card. Link??

* Barclays says was ?singled out? in tax row. Reuters. British bank Barclays said tax authorities singled it out for unfair treatment in a tax row earlier this year that damaged the bank?s reputation. Britain said in February it would close two ?aggressive tax avoidance schemes? used by Barclays and retrospectively applied a new tax to a bond buyback the bank did in December. Link

* Britain announces ?pasty tax? U-turn. Reuters. Britain?s Conservative-led government is to modify a levy on hot takeaway food after months of criticism that its planned ?pasty tax? showed it was out of touch with ordinary people. A Treasury spokeswoman said that Value Added Tax (VAT) would not be applied to hot takeaway food that is cooling down after being cooked ? for example the popular Cornish pasties which shops rarely sell straight from the oven. Link??

* Taiwan finance minister quits over scaled-back tax plan. Faith Hung ? Reuters. Taiwan?s finance minister resigned on Tuesday in protest against a ruling party proposal to sweeten a capital gains tax plan she had authored that has drawn the ire of stock investors. Under the Nationalist party?s plan, investors have the choice of paying the tax when the market trades above 8,500 points or they can add their stock trading profits to their annual income. The tax rates are also much lower. Link??

* Financial group looking at changes to simplify accounting standards. Danielle Douglas ? The Washington Post. The Financial Accounting Foundation, which oversees the boards that set guidelines at the state and federal level for tracking the financial performance of U.S. companies, has established the Private Company Council. The council is charged with identifying, considering and voting on any proposed changes to Generally Accepted Accounting Principles. For now, the Financial Foundation is in the process of pulling together a 9- to 12-member team to serve on the council. The foundation will put out a call for nominations in early June. Link??

* Improvised explosive device tax. The Wall Street Journal opinion. Several of the Affordable Care Act?s worst tax increases are scheduled to begin in 2014, such as the new excise tax on medical devices. The 2.3 percent levy applies to the sale of everything from cardiac defibrillators to artificial joints to MRI scanners. The device tax is supposed to raise $28.5 billion from 2013 to 2022, and it is especially harmful because it applies to gross sales, not profits. Companies at make-or-break margins could be taxed out of existence, especially in an intensely competitive industry where four of five businesses are start-ups or midsized. Link

* Republican Keynesians. Bruce Bartlett ? The New York Times opinion. Mitt Romney, in an interview with Time magazine, said he expressed concern about the impending fiscal contraction on Jan. 1, 2013, when the Bush-era tax cuts expire and various large cuts in spending are scheduled to take place ? a result of last summer?s budget deal. One would think that Romney would embrace this huge deficit reduction and say, ?Bring it on!? After all, his party has long asserted that deficits drain capital from the economy that would better be put to use by the private sector. Romney is in fact embracing Keynesian economics. Link

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Tool-wielding robots crawl in bodies for surgery

In this April 18, 2012, photo, Carnegie Mellon University professor Howie Choset, right, stands beside a robot as staff researcher Florinan Enner uses a controller to demonstrate how it climbs up a tubular armature at their lab on campus in Pittsburgh. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer and other diseased organs. (AP Photo/Keith Srakocic)

In this April 18, 2012, photo, Carnegie Mellon University professor Howie Choset, right, stands beside a robot as staff researcher Florinan Enner uses a controller to demonstrate how it climbs up a tubular armature at their lab on campus in Pittsburgh. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer and other diseased organs. (AP Photo/Keith Srakocic)

In this April 18, 2012, photo, Carnegie Mellon University professor Howie Choset, right, stands behind a robot as staff researcher Florinan Enner uses a controller to demonstrate how it moves at their lab on campus in Pittsburgh. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer and other diseased organs. (AP Photo/Keith Srakocic)

In this April 18, 2012, photo, Carnegie Mellon University professor Howie Choset stands behind a robot demonstrating how it climbs up a tubular armature at their lab on campus in Pittsburgh. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer and other diseased organs. (AP Photo/Keith Srakocic)

This April 18, 2012, photo made with a fisheye lens shows one of the robots being developed at Carnegie Mellon University penetrating a model of a heart in Pittsburgh. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer and other diseased organs. (AP Photo/Keith Srakocic)

PITTSBURGH (AP) ? Imagine a tiny snake robot crawling through your body, helping a surgeon identify diseases and perform operations.

It's not science fiction. Scientists and doctors are using the creeping metallic tools to perform surgery on hearts, prostate cancer, and other diseased organs. The snakebots carry tiny cameras, scissors and forceps, and even more advanced sensors are in the works. For now, they're powered by tethers that humans control. But experts say the day is coming when some robots will roam the body on their own.

"It won't be very long before we have robots that are nanobots, meaning they will actually be inside the body without tethers," said Dr. Michael Argenziano, the Chief of Adult Cardiac Surgery at New York-Presbyterian Hospital and Columbia University Medical Center in New York.

Argenziano was involved with some of the first U.S. Food and Drug Administration clinical trials on robotic heart surgery more than 10 years ago. Now he says snake robots have become a commonly used tool that gives surgeons a whole new perspective.

"It's like the ability to have little hands inside the patients, as if the surgeon had been shrunken, and was working on the heart valve," he said.

But Argenziano and experts in robotics say the new creations work best when they're designed for very specific tasks. "The robot is a tool. It is no different in that sense than a scalpel. It's really a master-slave device," he said.

Howie Choset has been researching and building robots, particularly snake robots, at Pittsburgh's Carnegie Mellon University for years.

Choset believes that his snake robot and others like it help reduce medical costs by making complex surgeries faster and easier. Choset says his new design is smaller and more flexible than earlier models: The diameter of the head is less than the size of a dime.

The size of surgical robots allows surgeons to operate with far less damage to the body, helping the patient heal faster. For example, instead of opening the entire chest up during heart surgery, a small incision is made, and the robot crawls inside to the proper spot.

Dr. Ashutosh Tewari of Cornell University Medical Center has used robotic tools to perform thousands of prostate operations. He said the precision of the tiny robotic tool is vital not just to cutting out cancerous tumors, but to seeing exactly what nerves to leave intact.

Tewari said he's most excited about the potential for surgical robots to do things humans can't do. He said the variety of sensors available for surgical robots keeps expanding, even as they get smaller. He said they may one day be able to test chemicals or blood in the body, or even the electrical connections in nerves.

Choset has also built larger snake robots designed for search and rescue, or just exploration. They can climb poles or trees and then look around through a camera in the head, and slither through places humans can't reach.

"We sent our snake robots into these caves off the coast of the Red Sea to look for evidence of ancient Egyptian ships," he said. "To me archaeology is like search and rescue, but everyone's been dead for 5,000 years," reducing the pressure.

Another expert at Carnegie Mellon stresses that there's still an enormous gap between humans and even the most high-tech robots. Manuela Velosa noted that robots have been built that excel at one or two tasks ? but not at the variety of tasks humans perform without even thinking.

Velosa has been building robots that ask humans for help when they don't know what to do, as well as teams of robots that play soccer against each other. Sometimes, the robots surprise her.

During one soccer game against robots from another university, the Carnegie Mellon team scored on a particular play. That sent a positive signal to the robot's computers, which are designed to reward success and discourage failures in the game.

Her robots then tried the play again ? and scored again. It turned out they had discovered a programing flaw in the other team of robots, just like some sports teams find a flaw in their opponents.

In the second half Velosa's robot's kept using the same play, scoring every time, and thus reinforcing the tendency to try the play over and over. The robots crushed the other team.

"It was programmed by me, but it looked to me as if they learned," she said. "I believe we are much closer to having robots be able to coexist with humans. The beautiful thing is you see the robots learning."

Associated Press

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UN Security Council condemns Syria massacre

Syria blamed terrorists for the Sunday massacre of more than 100 people, including children. Washington isn't buying it. NBC's Richard Engel reports.

By NBC News and msnbc.com news services

Updated at?6:01 p.m. ET -- The U.N. Security Council on Sunday unanimously condemned the Syrian government for heavy-weapons attacks on the town of Houla, the site of a massacre of at least 108 people, including many children, the council president said.
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"The Security Council condemned in the strongest possible terms the killings, confirmed by United Nations observers, of dozens of men, women and children and the wounding of hundreds more in the village of (Houla), near Homs, in attacks that involved a series of government artillery and tank shellings on a residential neighborhood," the non-binding statement said.
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"The Security Council also condemned the killing of civilians by shooting at close range and by severe physical abuse," said the statement, which was read out after the council's three-hour emergency meeting by Azerbaijan's Deputy U.N. Ambassador Tofig Musayev.

Facing mounting international outrage over the killings, Syria earlier on Sunday accused rebels of carrying out the massacre.

Images of bloodied and lifeless young bodies, lain carefully side by side after the onslaught on Friday, triggered shock around the world and underlined the failure of a six-week-old U.N. cease-fire plan to stop the violence.

Syrian authorities blamed "terrorists" for the massacre, among the worst carnage in the 14-month-old uprising against President Bashar al-Assad, which has cost about 10,000 lives.

"Women, children and old men were shot dead. This is not the hallmark of the heroic Syrian army," Foreign Ministry spokesman Jihad Makdesi told reporters in Damascus.

Makdesi said Syrian security forces were in their local bases Friday when they were attacked by "hundreds of heavily armed gunmen" firing mortars, heavy machine guns and anti-tank missiles, staring a nine-hour battle that killed three soldiers and wounded 16.

Opposition activists said Assad's forces shelled Houla after a protest and then clashed with fighters from the Sunni Muslim-led insurgency.

Activists say Assad's ?shabbiha' militia, loyal to an establishment dominated by members of the minority Alawite sect, then hacked dozens of the victims to death, or shot them.

Maysara al-Hilawi said he saw the bodies of six children and their parents in a ransacked house in the town.

"The Abdelrazzak family house was the first one I entered. The children's corpses were piled on top of each other, either with their throats cut or shot at close range," Hilawi, an opposition activist, said by telephone from the area.

"I helped collect more than 100 bodies in the last two days, mostly women and children. The last were six members of the al-Kurdi family. A father and his five kids. The mother is missing," he said.

Damascus protesters shot dead
Syrian forces shot dead two men on Sunday at a protest in Damascus against the killings in Houla, opposition activists said. The men's funerals also turned into demonstrations.

Footage broadcast by activists in the Damascus suburb of Yalda showed a crowd of hundreds at one of the men's funerals shouting "the people want the downfall of the regime."

Shaam News Network / AFP - Getty Images

A picture released by the Syrian opposition's Shaam News Network allegedly shows smoke billowing following a blast targeting a Syrian security forces vehicle on the ringroad outside the Damascus Mazze district early Sunday.

The U.N. Security Council held an emergency meeting Sunday to discuss the killings.

The United Nations believes that at least 108 people were killed in?the massacre, the U.N. peacekeeping chief Herve Ladsous told the meeting.

U.N. observers in Syria have confirmed that artillery and tank shells were fired, U.N.?Secretary-General Ban Ki-moon said in a letter to the Security Council.

The letter, which was obtained by Reuters, said the observers "viewed the bodies of the dead and confirmed from an examination of ordnance that artillery and tank shells were fired at a residential neighborhood."

Western countries and Arab states opposed to Assad put the blame for the deaths squarely on Damascus.

The Gulf Cooperation Council of Sunni-led monarchies accused Assad's soldiers of using excessive force and urged the international community to "assume its responsibilities to halt the daily bloodshed in Syria."

EU foreign policy chief Catherine Ashton spoke of a "heinous act perpetrated by the Syrian regime against its own civilian population" in a statement on Sunday. The head of the European parliament said it could amount to a war crime.

'Rule by murder'
"We are horrified by credible reports of targeting killing, including stabbing and ax attacks on women and children in Houla. These acts serve as a vile testament to an illegitimate regime that responds to peaceful political protest with unspeakable and inhuman brutality," U.S. National Security Council spokesman Tommy Vietor said Sunday.

U.S. Secretary of State Hillary Clinton demanded that those who carried out the killings be held to account.

"The United States will work with the international community to intensify our pressure on Assad and his cronies, whose rule by murder and fear must come to an end," she said.

France said it would call a meeting of the Friends of Syria, a group of Western and Arab countries keen to see Assad removed.

Britain said it would summon Syria's envoy over the massacre and that it would call for a meeting of the U.N. Security Council in coming days.

The United Arab Emirates requested an urgent meeting of the Arab League, whose head, Nabil Elaraby, urged the U.S. Security Council to stop the killing.

Former U.N. Secretary-General Annan is to brief the U.N. Security Council on Wednesday and is likely to be guided on who is responsible by reports from U.N. observers in Houla.

Although the cease-fire plan negotiated by Annan has failed to stop the violence, the United Nations is nearing full deployment of a 300-strong unarmed observer force meant to monitor a truce.

The plan calls for a truce, withdrawal of troops from cities and dialogue between government and opposition.

Syria calls the revolt a "terrorist" conspiracy run from abroad, a veiled reference to Sunni Muslim Gulf powers that want to see weapons provided to the insurgents.

The United Nations has accused Assad's forces and insurgents alike of grave human rights abuses, including summary executions and torture.

NBC News contributed to this report from Reuters.

More world news from msnbc.com and NBC News:

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Rant Sports MLB Power Rankings For Week Eight

Published: About an hour ago

Joy R. Absalon - US Presswire

It is time to continue our?MLB?Power Rankings for the 2012 season, which will continue to focus on the top 10 teams in the majors.

Texas Rangers?(This Week: 1, Last Week: 1) -?The Rangers had struggled to score runs over the past week, but they more than made up for it against the Toronto Blue Jays. Josh Hamilton hit another homer, and the Rangers cruised to a 14-3 victory. Games like these are why the Rangers remain #1 on our MLB Power Rankings.

Los Angeles Dodgers?(This Week: 2, Last Week: 3) -?Matt Kemp and Clayton Kershaw get most of the attention, but how about the season by AJ Ellis? He?s got a 944 OPS with an insane 444 OBP, and he?s transformed himself into one of the best catchers in the game. He won?t keep hitting like this, but Ellis is one of the driving forces behind the Dodgers surprising best record in the majors.

Baltimore Orioles?(This week: 3, Last Week: 4) -?Adam Jones gets his extension and drives in a pair of runs. With Jason Hammel close to free agency he has to be next on the Orioles list. At 29-17, the Orioles are one of the best team in the majors, and remain in the top 3 for our MLB Power Rankings.

Tampa Bay Rays?(This Week: 4, Last Week: 7) -?It?s amazing that they?re a game out of first without Evan Longoria. Alex Cobb has done a fantastic job filling in for the injured Jeff Niemann, winning both of the games he has pitched so far.

Washington Nationals?(This Week: 5, Last Week: 6) -?Their offence is one of the worst in the majors, but at least Bryce Harper is starting to hit again. They took game one of a big series against the Atlanta Braves, who are in a freefall right now.

Atlanta Braves?(This Week: 6, Last Week: 2) -?They got swept by the Reds in a four game series, and now they have to beat Stephen Strasburg in order to stay close to the Nats. Chipper Jones went back on the disabled list, and nothing is going right for the Braves anymore. Given how tight the NL East is, another loss could put them in fourth. A bad week might push them out of the top 10 of our MLB Power Rankings.

Cincinnati Reds?(This week: 7, Last Week: N/A) -?A sweep of the Braves and a surprising lead of the NL Central puts them back on our MLB Power Rankings. They?re winning with good pitching and the continued MVP calibre production of Joey Votto. He?s been one of the best players in the National League, and if the Reds make the playoffs don?t be surprised if Votto takes home his second MVP award.

St. Louis Cardinals?(This Week: 8, Last Week: 5)?-?What a difference a week makes. Last week the Cardinals were unstoppable, and now they trail the Reds by half a game. They got swept by the Dodgers and lost 2/3 to the Philadelphia Phillies. They?ve lost Lance Berkman for another 8-10 weeks, and then they lost his replacement Matt Carpenter. Next week doesn?t get any easier, as they face Atlanta for a 3 game set.

New York Yankees?(This Week: 9, Last Week: 9) -?With the victory last night they?re back in third place in the AL East. Which doesn?t sound very impressive, but right now that?s good enough to be the second wild card team. How about the season by Curtis Granderson? 14 homers, 25 RBI, and a 912 OPS. Everybody talks about the successful seasons of Derek Jeter and Alex Rodriguez, but somehow Granderson always flies under the radar. It?s a shame too, because he?s one of the best players on a loaded Yankees squad.

Cleveland Indians?(This week: 10, Last Week: 10) -?Is it too early to say Shin-Soo Choo is back? With a 900 OPS in May, one of the best all around outfielders in the game is starting to heat up after a forgettable 2011 season. And Cleveland couldn?t be any happier with the timing, as their lead is down to 2.5 games over the Chicago White Sox.

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Strengthening Social media Media For the Growing MLM Income ...

Network marketing, known as the relationship of distribution, plus much more popularly often called MLM, can be a business technique of directly marketing to customers. Called by many names, the independent salespeople in MLM would be the distributors, sales consultants, independent business agents, business agents or franchise owners. They may be un-salaried and represent parents company. Getting money using a commission basis comparable to the level of volume they offer, they?ve created his or her client base then sell to consumers through networking. The affiliate marketing system is a very good way to network for some other marketers, where placing website links on each others webpage is usually traded.

Having the legacy of an disgrace attached to this industry that stinks on the illegitimate pyramid schemes based on recruitment, MLM is not a online business opportunity right for everyone. This is the reason we have seen lots of people fearing MLM while they are not aware of whether a certain home based business is really a legitimate revenue stream you aren?t. The truth is, legitimate multi level marketing opportunities just pay commissions for any products offered. They don?t pay money for the recruitment of other members.
The 70% rule is one method to look for the legitimacy on the multi level marketing. This practice follows the general rule of placing another order while using company only after selling 70% with the current inventory. This avoids inventory loading and ensures that bonuses are usually not improperly gained. However, you?ll find different variations upon the 70% rule based on this business. While joining a Multilevel marketing business opportunity, that you are to view on what the commission works, whether you can find some form of 70% rule in place and have absolutely to scrutinize the rules and regulations very carefully to be sure it is actually legitimate.

MLM company is information on developing social networking sites and there?s no shortage of the way to do this. The world wide web based social network strategy is the greatest and a lot proven technique to enhance your profits for your prospering internet business. Being the most famous and successful technique, consultants can get out in the internet to see and also be seen. You need to use this directory of top internet to improve your prospective base.

LinkedIn is actually a social network site to select from your way to a lot professionals serving different industries. 43Things is another social media link for professionals like your-self whorrrre goal oriented. Twitter is actually a social messaging utility for staying connected in real-time and is a favorite micro blogging service where information about your MLM can be given to your followers.

Anything you bookmark can be shared with others and all that you?ve saved might be bookmarked by others, whose details could be kept on top of, while using Creating of social bookmarks system. You thus be able to view who?s got bookmarked your blog post or homepage. A social bookmark submitting tool shall be put on your website to permit individuals who use submitting of social bookmarks to flag your site.

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2-minute expert: How to avoid blurry photos

9 hrs.

Sean Captain, TechNewsDaily managing editor

This holiday weekend, you may be traveling to see family, taking a scenic day trip or going to the neighbor's BBQ.

All are good photo opportunities ? whether with a "real" camera or a cellphone.?

Here are some tips to make the pictures better. Nothing too tricky: They assume you use the camera's auto setting or make minor adjustments.?[6 Tips to Use Instagram Like a Pro]

How do I make sure photos are in focus?

Often, something is in focus, but not the thing you wanted. Many modern point-and-shoot cameras and some cellphones have a face-detection mode that you can select to recognize multiple faces and optimize the focus (as well as exposure and color) for them.

If you don't have this mode, or you want to focus on something else, adjust the focus point to be more precise.?

Newer iPhones make this easy: Simply point on the screen to the part you want to be sharp.?

On other cameras, you can often change the default ? which makes a compromise so that everything is sort of sharp ? and instead chose a smaller focus point or area.?

To do this, you may have to take the camera out of auto mode and chose program mode, typically labeled "P" on the selector. [Expect to See Photo-Sharing in Ever-More Apps]

They still look blurry. What gives?

You may still get a blurry picture if you are in low light because the camera has to keep the shutter open for a relatively long time.?

The trick here is to minimize movement. If you are buying a new point-and-shoot, get one with optical image stabilizations (OIS), which moves either the lens or the image sensor to compensate for jitters.

With or without OIS, try holding the camera steadier. Make sure you have firm footing, and keep your arms close to your body when you shoot. If you can, hold the camera against something such as a pole or a tabletop. [What Makes a High-Quality Camera?]

More from TechNewsDaily:

Copyright 2012 TechNewsDaily, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Types of Retirement Plans | Life-Health-Happiness

We all know that there is a growing need in this country to take our retirements into our own hands if we want the funds necessary to have any quality of life upon retirement. The problem is that most of us have no idea where to begin when it comes to financial retirement planning or investing. The sad news is that for most of our lives retirement was something that was taken care of if we put in an honest lifetime of work. However, the climate has changed and the retirement funds that many of us have labored to pay for the vast majority of our lives are slipping away.

The good news is that this need has not gone unnoticed by the powers that be and while they aren?t offering solutions for the funds we?ve already invested or in salvaging what is left of the failing system, they are empowering people to take some control for their personal retirements by offering investment options and strategies that provide tax benefits along the way in order to reward you for your efforts.

The four common types of retirement plans include 401(K) plans, Keough Plans, IRAs (individual retirement accounts), and qualifying pension or profit sharing plans offered by corporations. In most retirement plans, the contributions to those plans are tax deductible and taxes aren?t paid on these plans until the funds are received and retirement payment begins. You should be careful of your investments and guard them well as there are often hefty penalties involved when you take funds out of your retirement funds before you actually retire.

These of course are not the only types of investments you can make for your golden years and it never hurts to have more eggs in many baskets. The more the merrier in most cases. My personal preference for investing is real estate. This is an investment that you can actually see and reach out and touch. It is also an investment that often gets overlooked when planning for retirement, though when you consider it is an excellent choice. Property values are much lower today than they will be ten, twenty, or fifty years from now. This means the sooner you buy the property the more it will be worth (in theory) when you retire. The thing to remember is that property investing, like other types of investing, requires some degree of risk. You need to learn as much as you can about the process and discuss your interest with a financial advisor before you make any major decisions concerning your retirement investments.

There are more traditional investment methods you may want to consider as well. Mutual funds and the stock market are great ways to invest your money, build a decent portfolio, and increase your net worth. This type of investing also carries some degree of risk and isn?t always considered financial retirement planning but more along the lines of simple financial planning.

The thing to remember is that it is always good to have a plan. For this reason, I strongly encourage you to engage the services of a good financial planner. He or she can help you navigate the tricky language that is involved in many transactions, set realistic and obtainable retirement goals according to your needs as well as your means, and offer excellent advice and guidance on other investment ventures you may wish to pursue. In other words, a good financial planner can help you plan for your retirement.

When it comes to the world of finance, many of us are far from experts. We seek legal advice from attorneys, tax advice from accountants, and medical advice from doctors yet very few of us go to financial planners when planning our financial retirement. In many ways it makes little sense to approach our futures so carelessly and yet this is not something that our parents and grandparents would have done so there is no precedence for doing so. The problem is that money is such a limited commodity in this world, we are living longer than ever before, and we are enjoying much more mobility in our golden years than in times long past. We now need expert advice and guidance in order to insure that we are in the best possible position when the time comes to face our own retirements.

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VicMan Visage Lab for iPhone and iPad review

VicMan Visage Lab for iPhone is an app that will give your portraits a complete makeover with just the tap of a button. I'm always fairly skeptical of these types of apps because they have the potential to produce results that look very fake and overdone, but not VicMan Visage Lab -- the results are very good!

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Getting Out in the Community

BY GAVAN CONWAY ? During the recent visit by Kaipo Ho and Marsha Kapu, the Australian Corporate Office staff decided to undertake some community work for a day.?The office was divided into two groups each having the task of finding a community organisation where they could volunteer for a day.

Marsha joined the first group who spent the day with Friends of Federation Walk, a Gold Coast City initiative for the regeneration of the vegetation on The Spit, which is a beach and dune area near Surfers Paradise. Their objective is to maintain Federation Walk Coastal Reserve as a natural Public Open Space for the benefit of the community. It is a restoration and low impact conservation project that the community can be actively involved in. Their duties included planting over 50 new trees and cleaning up pathways along the foreshore.

The second group, which included Kaipo, went to the Animal Welfare League (AWL) where they helped to clean out pens and walk dogs. Of course, there were one or two puppies and kittens to play with! The AWL has a policy of not euthanizing stray animals and attempts to find new homes for all animals in their care. On the day we visited the shelter, it was temporary home to dogs, cats, rabbits, guinea pigs, chickens and an uninvited green tree snake (frightening but non-venomous).

The Foreshore Care Group - Stephen Rowe, Frances Hale, Bronwyn Marshall, Sophie Secombe, Shelley Flynn, Marsha Kapu, Nicky Chapman and Holly Norball

Cleaning up the foreshore pathways ? Frances Hale, Marsha Kapu and Sophie Secombe

Grant James, Sharon Godfrey, Gavan Conway, Amanda Gaudion, Kaipo Ho, Lisa Tzanetopoulos, Tracey Dumble and Woody, a very strong, two-year old labrador

Gavan Conway with a Greyhound named Hugo, a special ambassador for the shelter who often visits schools, aged care facilities and hospitals

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Thousand-Year-Old Mummies Found in Peru

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Home inspection in Mississauga

Home inspection in Mississauga is being offered by numerous companies dealing in this very business. Mississauga is a very populous city in Canada and you can easily find out such services over here. There are loads of houses being bought and sold every day over here. And, home inspector services get to be hired often in this very regard.

Home inspection in Mississauga is one such service that has become really essential whether you are going to buy or sell a house. It happens many times that you take a professional expert or a friend of yours in case of buying a car. You feel the need to be assured of the fact that the car you are going to buy is free of all sorts of serious concerns.

This is the same feel that you need to have while going to buy a used house. You need a detailed evaluation, giving you the surety that there are no safety concerns, no pending repairs, no structural hazards in that very house. And, all these features cab not be located by an ordinary eye.

There needs to be a professional one who can deduct the problem under the covers of "all set". This kind of professional help is being offered by the home inspection companies operating in Mississauga.

Home inspection is just not necessary for the used homes only. You need to be sure of all the above mentioned features even if you are going to buy a brand new house. So, the need of home inspection is all important and you cannot ignore it if you are intending to buy even a new house.

You can easily find out such services being offered in your nearby areas. Internet is one such medium that can give you the access to all the required information. You can conduct an online search and can find out numerous such companies.

And, if you can make a list of four to six such companies and then can compare and contrast their services and charges, this can earn you an affordable deal as well. But, be sure of the fact that a company needs to be legal and expert.

Home inspection in Mississauga can be hired even if you intend to sell your house. This is one such service that not only can make you aware of the short comings in a house but can save you from both financial and emotional inconvenience later on.

So, do invest in this service if you are considering buying/selling a house. You will spend a little but will get a big return.

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UK's Cameron defends role in Murdoch takeover deal

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Denver Auto Repair: Wheel Bearing Repair Denver

Wheel Bearing Repair Denver

It is a dirty job, but someone has got to do it; at Buchtel Motors we have got your wheel bearing repair covered in Denver! It is a necessary process after so many miles of driving that wheel bearing repair should be done, but by a certified technician who can do it properly and detect if there are other issues to be repaired as well.? Each component has its specific place and requires skill to disassemble and reassemble properly. Let our team at Buchtel Motors take on that job. We are the experts at wheel bearing repair and we can have your vehicle back to you ready to drive quickly in Denver. It is not worth the risk of having an amateur do the work. The only way to ensure proper wheel bearing repair is to have the professionals at Buchtel Motors handle the task from start to finish.? We will make you feel right at home when you come in to our family owned and operated auto repair center, with friendly assistance and professional wheel bearing repair in Denver. Call or come by to schedule the best time to bring your auto in to Buchtel Motors.?

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